Description

Granada Crystallization Box^® (GCB) is a simple device to crystallize protein and other biological macromolecules by counter-diffusion method. GCB consists of 4 elements made of polystyrene:

A reservoir to introduce the gel
A guide to hold capillaries
A cover
A holder to maintain the boxes

The GCB has been designed to be used in four different ways:

To grow crystals inside gels under diffusion controlled mass transport.
To grow protein crystals inside capillaries with un-gelled precipitating agent by the counter-diffusion technique.
To grow protein crystals inside capillaries with gelled precipitating agent by the counter-diffusion technique.
To grow protein crystals inside capillaries by the batch method.

Main characteristics

The role of viscous fluids, gels and/or micro-gravity is enhanced by using capillary volumes.

From 500 nanoliters to 100 nanoliters of protein solutions depending on the inner diameter of the capillaries.

One capillary scans the same precipitation region than hundreds of drops.

Transport your precious crystals in your pocket!

Crystals grow inside x-ray capillaries
If desired, no handling of crystals
Usable for cryo-crystallography

Triana Science & Technology offers GCBs in packages of 20 boxes

To make an order, just send us an email to triana@trianatech.com with a list of the required products and services you need.

1. J.M. García-Ruiz, Counterdiffusion Methods for Macromolecular Crystallization. Methods in Enzymology, Vol. 368 (2003) 130-154.
2. Granada Crystallisation Box: a new device for protein crystallisation by counter-diffusion techniques. Garcia-Ruiz JM, Gonzalez-Ramirez LA, Gavira JA, Otalora F. Acta Crystallogr D Biol Crystallogr. 2002 Oct;58 (Pt 10 Pt 1):1638-42.

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